Anticonvulsant activity of butanol fraction of methanol root bark extract of Securinega virosa Roxb (ex Willd) Baill. in laboratory animals

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Isolation of bergenin from the root bark of Securinega virosa and evaluation of its potential sleep promoting effect

Objectives: Securinega virosa Roxb (Ex Willd) Baill (Euphorbaiceae) root bark has been reportedly used in African traditional medicine in the management of mental illnesses. Previously, the sleep-inducing potential of the crude methanol root bark of Securinega virosa extract and its butanol fraction have been reported. The study aimed to isolate and characterize the bioactive constituent that m...

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Isolation of bergenin from the root bark of Securinega virosa and evaluation of its potential sleep promoting effect.

OBJECTIVES Securinega virosa Roxb (Ex Willd) Baill (Euphorbaiceae) root bark has been reportedly used in African traditional medicine in the management of mental illnesses. Previously, the sleep-inducing potential of the crude methanol root bark of Securinega virosa extract and its butanol fraction have been reported. The study aimed to isolate and characterize the bioactive constituent that ma...

متن کامل

isolation of bergenin from the root bark of securinega virosa and evaluation of its potential sleep promoting effect

objectives: securinega virosa roxb (ex willd) baill (euphorbaiceae) root bark has been reportedly used in african traditional medicine in the management of mental illnesses. previously, the sleep-inducing potential of the crude methanol root bark of securinega virosa extract and its butanol fraction have been reported. the study aimed to isolate and characterize the bioactive constituent that m...

متن کامل

Behavioural effects of the methanolic root bark extract of Securinega virosa in rodents.

Securinega virosa is used traditionally as sedative in children and in mental illnesses. In this study, the behavioral effects of methanolic root bark extract of S. virosa were investigated in mice. The results revealed that the extract significantly (P<0.05) and dose-dependently reduced the onset and prolonged the duration of sleep. The extract significantly (P<0.05) decreased exploratory acti...

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Cardiovascular activity of the n-butanol fraction of the methanol extract of Loranthus ferrugineus Roxb.

We investigated the vascular responses and the blood pressure reducing effects of different fractions obtained from the methanol extract of Loranthus ferrugineus Roxb. (F. Loranthaceae). By means of solvent-solvent extraction, L. ferrugineus methanol extract (LFME) was successively fractionated with chloroform, ethyl acetate and n-butanol. The ability of these LFME fractions to relax vascular s...

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ژورنال

عنوان ژورنال: Journal of Medicinal Plants Research

سال: 2013

ISSN: 1996-0875

DOI: 10.5897/jmpr12.1209